Role of Stem Cell Niche in the Maintenance of Hematopoietic Stem Cells

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The hematopoietic stem cell niche.

Hematopoietic stem cells (HSCs) possess the ability to self-renew and to differentiate to mature progeny along multiple different hematopoietic lineages. The function of HSCs depends upon the signals from surrounding cells found within the highly specialized microenvironment termed the hematopoietic stem cell niche. Understanding and exploiting the HSC niche is a goal of basic scientists and cl...

متن کامل

Pediatric Hematopoietic Stem Cell Transplantation

The introduction and evolution of hematopoietic stem cell transplantation (HSCT) could be traced back to 1950s, to the studies on interactions among irradiation, covering spleen and bone marrow from it and injection of bone marrow cells. Today, HSCT is considered a well-established, effective and promising means of therapy for various malignant and non-malignant medical conditions, both in chil...

متن کامل

Hematopoietic Stem Cell Niche: Role in Normal and Malignant Hematopoiesis

A stem-cell niche can be defined as a spatial structure in which stem cells are housed and maintained by allowing self-renewal in the absence of differentiation. The concept of the stemcell niche was initially proposed in invertebrates where they were first characterized; the control of germ line stem cell maintenance and differentiation was observed in ovarian and testicular D. melanogaster ni...

متن کامل

SnapShot: The Hematopoietic Stem Cell Niche

O sx O sx O sx O sx O sx O sx O sx O sx O sx +++++ p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce...

متن کامل

Differentiation of Mouse Embryonic Stem Cells into Hematopoietic Cells

Purpose: Differentiation of Mouse embryonicstem cells into Hematopoietic cells. Materials and Methods: In this study, we used EB formation system for Hematopoietic differentiation of mouse embryonic stem cell (Royan B1) in suspension culture. EBs cultured in medium with Hematopoietic inducer cytokines (SCF, TPO, GMCSF, IL3, Flt3 and EPO) .presence of hematopoietic differentiated cell assessed ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Inflammation and Regeneration

سال: 2007

ISSN: 1880-9693,1880-8190

DOI: 10.2492/inflammregen.27.117